Raf Kinase Inhibitory Protein or RKIP was initially identified as a Raf-1 binding protein using the yeast 2-hybrid screen.RKIP inhibits the Scrapers activation phosphorylation of MEK by Raf-1 by competitively inhibiting the binding of MEK to Raf-1 and thus exerting an inhibitory effect on the Raf-MEK-Erk pathway.RKIP has been identified as a metast
The accurate diagnosis of gout frequently constitutes a challenge in clinical practice, as it bears a close resemblance to Pregnancy Test other rheumatologic conditions.An undelayed diagnosis and an early therapeutic intervention using uric acid lowering therapy (ULT) is of the utmost importance for preventing bone destruction, the main point of ma
Melioidosis is an emerging infection in Brazil and neighbouring South American countries.The wide range of clinical presentations include severe community-acquired pneumonia, septicaemia, central nervous system infection and less severe soft tissue infection.Diagnosis depends heavily on the clinical microbiology laboratory for culture.Burkholderia
Abstract The drag loss behavior of a disengaged wet clutch is influenced, among other things, by the movement of the plates.Therefore, knowledge about the plate movement is essential for investigating and optimizing the drag loss behavior.This paper presents a methodology for image-based measurement of plate movement in disengaged wet clutches.A dr